Dr Sean Preston is Medical Director and Director of Endoscopy at The Princess Grace Hospital and Chair of Digestive Diseases and Renal Department for HCA Healthcare UK. 

He graduated from St Mary's Hospital Medical School, Paddington in 1995. The majority of his postgraduate training was centred at Barts and the London NHS Trust (a major London Teaching Hospital), in addition to a year spent in Sydney as an Advanced Endoscopy Fellow, prior to his appointment as a Consultant at Barts in 2006 where he continues to work. His clinical practice includes the diagnosis and treatment of gastro oesophageal reflux disease (heartburn), Barrett's oesophagus, irritable bowel syndrome, inflammatory bowel disease, diarrhoea, constipation, bloating, in addition to diagnostic and therapeutic endoscopy of the oesophagus, stomach and colon. He has a keen interest in gut health and gastrointestinal microbiota (bacteria, viruses and fungi) and uses both diet, pre and probiotics in the achievement and maintenance of optimal conditions within the bowel. Clinical consultations are structured to allow patients sufficient time to explain all their symptoms and to fully understand for the cause of their concerns.

His PhD, undertaken at Cancer Research UK, London, outlined the role of stem cells in gastrointestinal cancers and led to several significant publications in the field.

He was Director of Endoscopy at Barts Health from 2008 - 2024 and is Deputy Director of the North East London NHS Bowel Cancer Screening Programme. His endoscopic expertise relates to gastroscopy, colonoscopy and endoscopic ultrasound and he is an accredited colonoscopist for the National Bowel Cancer Screening Programme (requiring a rigorous accreditation process and continual audit of key performance indicators). He has written numerous key papers and book chapters on gastrointestinal cancer and continues his research in Barrett's oesophagus.

Dr Preston also featured in the 2013 Tatler Doctors Guide of Britain's top 250 consultants and is in 2024's elite group of Spears 500 Top Recommended UK Private Doctors and Surgeons. He was President of the Gastroenterology and Hepatology Section of the Royal Society of Medicine from 2015-2017 and was previously Chairman of the Specialists' Committee for the Independent Doctors' Federation.

As a founding partner of London Digestive Health, within London Digestive Centre, he works within the framework of first class clinical team of other London Teaching Hospital Gastroenterologists, in addition to GI surgeons, Radiologists, Oncologists and a Dietician. 

It is important that HCA is transparent about our relationship with those doctors who provide us with clinical guidance on delivering the best possible care to patients and operating our hospitals safely and efficiently. We set out here some of the ways in which we work together and the amount we pay this doctor for such services.